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Looking for volunteers

Robotic Technologies for APATHy in Dementia: a Randomised Controlled Trial (RAPHAel)

NCT07404410 · Giovanna Zamboni · Updated 5 May 2026

What is being tested
telepresence robotic system; Pepper robot connected to a CAIR server; Occupational Therapy
For
Apathy; Apathy in Dementia
Kind of study
Tests a treatment or device on volunteers. No drug phase (a device or procedure study).
Who can join
Ages 40 years and older. About 75 people. The full rules are on the registry page.
Where
Italy (2 sites)
When
Starts or started 28 April 2026, ends 30 Nov 2026. Registered 11 Feb 2026.
Results
None posted yet.

In the researchers' words

The goal of this trial is to learn whether home-based robotic interventions can reduce apathy in people with cognitive decline. Apathy means reduced motivation, interest, or initiative in daily life. It is a common and distressing symptom in people with mild cognitive impairment (MCI) or dementia and can strongly affect both participants and their caregivers. This study will compare two different robotic interventions with standard occupational therapy. Researchers want to understand if these new technologies can help people become more engaged, motivated, and involved in everyday activities, and whether they also reduce stress and improve quality of life for caregivers. The main questions this study aims to answer are: * Do robotic interventions reduce apathy more than standard occupational therapy? * Are these robotic interventions easy to use and acceptable for people with cognitive impairment? * Do these interventions reduce caregiver stress and improve caregiver quality of life? Participants will be adults over 40 years of age with a diagnosis of mild cognitive impairment or dementia caused by a neurodegenerative disease, such as Alzheimer's disease, frontotemporal dementia, or dementia with Lewy bodies. All participants must show clinically relevant apathy and have a family member or caregiver who can support them during the study and answer questionnaires.…
ClinicalTrials.gov, NCT07404410

Sites

  • IRCCS "S. Maria Nascente"Milan, Italy, Italy
  • Azienda Ospedaliero Universitaria di ModenaModena, Italy, Italy