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Powered Exoskeleton-Assisted Walking in Persons With Spinal Cord Injury

NCT07884591 · IRCCS San Raffaele Roma · Updated 20 Oct 2026

What is being tested
Wearable Powered Exoskeleton
For
Spinal Cord Injuries (SCI); Muscle Spasticity as a Result of Spinal Cord Injury; Rehabilitation; Exoskeleton Device
Kind of study
Watches patients without assigning a treatment. No drug phase (a device or procedure study).
Who can join
Ages 18 years to 70 years. About 74 people. The full rules are on the registry page.
Where
Italy
When
Starts or started 1 Sept 2024, ends 15 May 2026. Registered 20 Oct 2026.
Results
None posted yet.

In the researchers' words

Spinal Cord Injury (SCI) represents a significant health challenge, particularly when it comes to the ability to walk. Among its many consequences, mobility impairment can not only directly impact quality of life but also cause a series of secondary problems, such as urinary tract problems, breathing difficulties, muscle contractures, joint stiffness, and resulting pain. These effects can manifest early, even at a young age, further increasing the physical and psychological burden of those affected. To address these challenges, the use of overground exoskeletons, such as the Ekso Bionics (USA), has attracted growing interest in both scientific research and clinical practice. The Ekso not only offers mobility but also represents a valuable resource for gait training, with potential direct and indirect benefits for the physical health and overall well-being of people with SCI. This study is a multicenter, retrospective, pre-post cohort study with the aim of evaluating the dose-dependent effects of exoskeleton-assisted walking training on level ground on spasticity and functional independence in individuals with spinal cord injury. The sample includes at least 70 participants with SCI underwed at least five sessions of walking training using the Ekso™ exoskeleton. Primary outcomes included changes in spasticity, measured by the aggregated Modified Ashworth Scale (MAS), and…
ClinicalTrials.gov, NCT07884591

Sites

  • IRCCS San RaffaeleRoma, Italy, Italy