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Comparison of Holmium Laser Enucleation of the Prostate and Robotic Water Jet Ablation for Benign Prostatic Hyperplasia
NCT07772232 · The Methodist Hospital Research Institute · Updated 19 Aug 2026
- What is being tested
- Device - HoLEP with MOSES 2.0; RWJA with Hydros Robotic System
- For
- Benign Prostate Hypertrophy(BPH); Lower Urinary Track Symptoms
- Kind of study
- Tests a treatment or device on volunteers. No drug phase (a device or procedure study).
- Who can join
- Ages 50 years to 80 years. About 100 people. The full rules are on the registry page.
- Where
- United States
- When
- Starts or started 3 Aug 2026, ends 3 Aug 2033. Registered 19 Aug 2026.
- Results
- None posted yet.
In the researchers' words
This study compares two FDA-approved surgical treatments for benign prostatic hyperplasia (BPH): Holmium Laser Enucleation of the Prostate (HoLEP) with MOSES 2.0 technology and Robotic Water Jet Ablation (RWJA) using the Hydros Robotic System. Men with BPH and prostate volumes between 50 and 180 mL will be randomly assigned to one of the two procedures. The study will measure changes in prostate volume, PSA, urinary flow, and bladder emptying at 12 months, along with safety, sexual function, continence, and healthcare utilization outcomes, which will be followed for up to 5 years after surgery.
Sites
- Houston MethodistHouston, Texas, United States