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Stroke Upper Limb Rehabilitation With Robot Operators: a Synergistic Approach for Human-Robot Interaction and Rehabilitative Trials.

NCT07768683 · Villa Beretta Rehabilitation Center · Updated 17 Aug 2026

What is being tested
Upper Limb robotic training
For
Stroke
Kind of study
Tests a treatment or device on volunteers. No drug phase (a device or procedure study).
Who can join
Ages 18 years and older. About 50 people. The full rules are on the registry page.
Where
Italy
When
Starts or started 8 May 2025, ends 12 May 2026. Registered 17 Aug 2026.
Results
None posted yet.

In the researchers' words

In clinical scenario, clinical scales and kinematic analysis are usually used for the evaluation of patients. However, these methods are limited, since they may suffer from the lack of objectivity and sensitivity. Synergies go beyond pure kinematics and allow to directly understand the neural mechanisms underlying the motor impairment. Synergy analysis has been exploited for understanding physiological mechanisms in healthy subjects, but only few studies analyzed muscle synergies on patients during rehabilitation. In order to translate this methodology to the clinical practice, there is the need of comprehensive and structured studies. However, only few pilot studies are available that analyzed synergies during rehabilitation. Thus, in this study we aimed at filling this gap by analyzing synergies during human-robot interaction when using an end-effector robot and an exoskeleton robot and by assessing in detail the modifications of synergies after robotic rehabilitation.
ClinicalTrials.gov, NCT07768683

Sites

  • Villa Beretta Rehabilitation CenterCosta Masnaga, Italy, Italy