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EVERiST: Impact of Image Detected Accessory Pudendal Artery on Erection Recovery After Nerve Sparing Prostatectomy
NCT07597798 · University College, London · Updated 19 May 2026
- What is being tested
- Robotic Radical Prostatectomy; Penile doppler ultrasound
- For
- Radical Prostatectomy; Erectile Dysfunction Following Radical Prostatectomy; Erectile Dysfunction Due to Arterial Insufficiency; Robotic Radical Prostatectomy
- Kind of study
- Watches patients without assigning a treatment. No drug phase (a device or procedure study).
- Who can join
- Ages 18 years to 79 years. About 40 people. The full rules are on the registry page.
- Where
- United Kingdom
- When
- Starts or started 15 Jan 2026, ends 15 Jan 2028. Registered 19 May 2026.
- Results
- None posted yet.
In the researchers' words
Prostate cancer is the most common cancer amongst men in the United Kingdom, and two common curative treatments are surgery to remove the prostate (radical prostatectomy) or radiotherapy. Both treatments can affect quality of life, mainly because of problems with erections and urinary leakage. Many men feel disappointed or regret their treatment choice because of changes in their sexual function. Surgeons often use a 'nerve-sparing' technique to reduce the risk of erectile dysfunction (ED), but many men still experience erection problems afterwards. A way to improve erectile function recovery after surgery further would be to identify accessory (additional) arteries to the penis. Up to one in three men have an extra artery called the accessory pudendal artery (APA). Preserving this artery during surgery may improve recovery of erections by protecting blood flow and reducing the risk or severity of ED. Until recently, surgeons could only try to see these arteries during the operation, and no study has tested whether they are preserved or whether this makes a difference. This has changed with the advent of imaging. Men already have an advanced MRI scan (called a multiparametric MRI) before prostate cancer treatment. These scans can also show whether an APA is present. In addition, robotic surgery, now the gold standard for radical prostatectomy, allows operations to be video…
Sites
- University College London Hospitals NHS foundation trustLondon, United Kingdom
