Monday, October 26, 2026 · Daily editionET --:--:--

Finished

Effect of Control Ventilation, PEEP, and PEEP With ARM in Robot-assisted Radical Prostatectomy

NCT07462689 · Ilsan Cha hospital · Updated 10 March 2026

What is being tested
PEEP group; PEEP + ARM group
For
Robot-Assisted Radical Prostatectomy
Kind of study
Tests a treatment or device on volunteers. No drug phase (a device or procedure study).
Who can join
Ages 20 years and older. About 58 people. The full rules are on the registry page.
Where
South Korea
When
Starts or started 1 Dec 2020, ends 29 Feb 2024. Registered 10 March 2026.
Results
None posted yet.

In the researchers' words

The goal of this clinical trial is to determine whether different ventilatory strategies improve oxygenation and hemodynamic stability in patients undergoing robot-assisted radical prostatectomy under general anesthesia. The study will also evaluate the safety and physiological effects of applying positive end-expiratory pressure (PEEP) and alveolar recruitment maneuver (ARM) during surgery. The main questions this study aims to answer are: Does the application of PEEP or PEEP combined with ARM improve intraoperative oxygenation compared with conventional mechanical ventilation? How do PEEP and ARM affect intraoperative hemodynamic parameters such as cardiac output and stroke volume during pneumoperitoneum and steep Trendelenburg positioning? Are there any adverse events associated with the use of these ventilatory strategies during surgery? Researchers will compare three ventilation strategies-conventional ventilation without PEEP, ventilation with PEEP alone, and ventilation with PEEP combined with ARM-to evaluate their effects on perioperative oxygenation and cardiovascular function. Participants will: Undergo robot-assisted radical prostatectomy under general anesthesia Be randomly assigned to receive one of three ventilatory strategies during surgery Receive standardized anesthetic management and intraoperative monitoring Have arterial blood gas analysis and…
ClinicalTrials.gov, NCT07462689

Sites

  • Hallym University Sacred Heart HospitalAnyang, Gyeonggi-di, South Korea