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Post-Operative Pain Relief: Zynrelef or Periarticular Injections in RATKA

NCT07430085 · Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) · Updated 6 July 2026

What is being tested
bupivacaine-meloxicam (extended release); Bupivacaine; Ketorolac; Lidocaine (drug)
For
Periarticular Block; Osteoarthritis (OA); Osteoarthritis (OA) of the Knee; Pain After Surgery; Knee Arthroplasty, Total
Kind of study
Tests a treatment or device on volunteers. Phase 4.
Who can join
Ages 18 years to 89 years. About 150 people. The full rules are on the registry page.
Where
Not stated
When
Starts or started 31 July 2026, ends 28 Feb 2028. Registered 24 Feb 2026.
Results
None posted yet.

In the researchers' words

Prospective Cohort of patients who are scheduled for a Robot Assisted Total Knee Arthroplasty (RATKA). A prospective survey of patient reported outcome measures (Numeric Rating Scale) will be obtained postoperatively of 72 hours, as well as at the postoperative opioid consumption after 72 hours.
ClinicalTrials.gov, NCT07430085