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Gait Training for Concurrent Optimization of Weight Mgt,bp Regulation and Functional Mobility

NCT07420595 · Iqra National University · Updated 19 Feb 2026

What is being tested
Weeks 1-6: EAGT (exoskeleton/end-effector devices; 30- 50% body-weight support, speed 1.5-2 km/h, ≥800-1200 steps/session). Weeks 7-12: CGT (overground walking, obstacles, stairs, dual-tasks).; Full 12 weeks CGT, progressing complexity and demands.
For
Cardiovascular Diseases; Stroke Sequelae
Kind of study
Tests a treatment or device on volunteers. No drug phase (a device or procedure study).
Who can join
Ages 45 years to 78 years. About 140 people. The full rules are on the registry page.
Where
Pakistan
When
Starts or started 1 Jan 2022, ends 1 Dec 2025. Registered 19 Feb 2026.
Results
None posted yet.

In the researchers' words

Stroke is a leading cause of long-term disability and death worldwide, with chronic survivors often experiencing gait disturbances (affecting up to 80%), reduced physical activity, and cardiometabolic comorbidities like obesity and hypertension. These increase risks of recurrent events and diminish quality of life. Electromechanically assisted gait training (EAGT) provides high-intensity, repetitive practice, while conventional gait training (CGT) enhances real-world functional transfer. Evidence gaps exist in the optimal sequencing of these approaches for concurrent improvements in weight management, blood pressure (BP), and mobility, particularly in high-risk chronic stroke populations. This multicenter RCT addresses these gaps by evaluating a sequenced hybrid protocol.
ClinicalTrials.gov, NCT07420595

Sites

  • IQRA National UniversitySwat, Peshawar, Pakistan