Looking for volunteers
RIght VEntricle Response to Major Lung Resection in VATS and Robotic Surgery
NCT07362342 · Istituto Clinico Humanitas · Updated 25 June 2026
- What is being tested
- Not stated
- For
- Lung Surgery; Right Ventricular Function
- Kind of study
- Watches patients without assigning a treatment. No drug phase (a device or procedure study).
- Who can join
- Ages 18 years and older. About 100 people. The full rules are on the registry page.
- Where
- Italy
- When
- Starts or started 20 Jan 2026, ends 1 Dec 2027. Registered 23 Jan 2026.
- Results
- None posted yet.
In the researchers' words
Major pulmonary resection is associated with high postoperative morbidity and mortality, mainly due to cardiorespiratory complications. Right ventricular (RV) function is closely related to pulmonary artery pressure and tone, and it is particularly sensitive to changes in afterload. An increase in RV flow resistance can lead to acute RV dilation and reduced left ventricular compliance, potentially progressing to cardiogenic shock. In a previous study (RIVER), it was observed that increased afterload following open thoracic surgery reduces RV function, although this impairment remains subclinical. The aim of this study is to investigate the same parameters in patients with severe cardiovascular comorbidities undergoing pulmonary resection via minimally invasive approaches (VATS and robotic surgery) compared to open thoracotomy.
Sites
- Humanitas Research HospitalRozzano, MI, Italy