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Robot/Laparoscopic-Assisted Transanal Transection Duhamel Versus Modified Soave Pull-Through for TCA
NCT07343622 · Zunyi Medical College · Updated 15 Jan 2026
- What is being tested
- Transanal Transection Duhamel operation; Modified Soave Pull-Through
- For
- Total Colonic Aganglionosis; Hirschsprung Disease; Duhamel; Soave
- Kind of study
- Tests a treatment or device on volunteers. No drug phase (a device or procedure study).
- Who can join
- Ages 1 Month to 14 years. About 50 people. The full rules are on the registry page.
- Where
- China
- When
- Starts or started 30 Jan 2026, ends 31 Dec 2027. Registered 15 Jan 2026.
- Results
- None posted yet.
In the researchers' words
Total colonic Hirschsprung disease (TCA) is the most severe form of Hirschsprung disease and is commonly managed with neonatal enterostomy followed by delayed definitive pull-through. Despite widespread use, the optimal reconstructive procedure for TCA remains uncertain. The Duhamel and modified Soave pull-through procedures are the two most frequently adopted techniques, each with distinct theoretical advantages and limitations regarding bowel function, enterocolitis risk, and anorectal physiology. With the increasing application of minimally invasive and robot-assisted surgery, both procedures have been further refined; however, robust comparative evidence, particularly for total colonic disease, is lacking. To date, no multicenter study has provided a detailed comparison of postoperative functional outcomes and Hirschsprung-associated enterocolitis between transanal transection Duhamel and modified Soave procedures. This multicenter study compares robot-assisted transanal transection Duhamel and modified Soave pull-through in patients with pathologically confirmed TCA after neonatal enterostomy, focusing on postoperative bowel function and enterocolitis incidence.
Sites
- Affiliated Hospital of Zunyi Medical UniversityZunyi, Guizhou, China
