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Looking for volunteers

Toripalimab in Combination With Standard Treatment for Human Papillomavirus (HPV) Positive Throat Cancer

NCT07290621 · University of Chicago · Updated 6 Feb 2026

What is being tested
Toripalimab; Carboplatin; Paclitaxel
For
Oropharyngeal Cancer
Kind of study
Tests a treatment or device on volunteers. Phase 2.
Who can join
Ages 18 years and older. About 30 people. The full rules are on the registry page.
Where
United States
When
Starts or started Feb 2026, ends Feb 2033. Registered 18 Dec 2025.
Results
None posted yet.

In the researchers' words

This is a single-center phase 2 study of to test how well the combination of toripalimab with chemotherapy followed by TORS or risk and response stratified de-escalated (chemo)radiotherapy works in patients with in HPV16+ locoregionally advanced oropharyngeal cancer (OPC).
ClinicalTrials.gov, NCT07290621

Sites

  • The University of Chicago Medicine Comprehensive Cancer CenterChicago, Illinois, United States