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Investigating the Mechanisms of Welwalk Robot in Restoring Motor Function of the Lower Extremities in Stroke Patients
NCT07057700 · Ruijin Hospital · Updated 10 July 2025
- What is being tested
- welwalk training; physical therapy
- For
- Stroke; Walking Impairment
- Kind of study
- Tests a treatment or device on volunteers. No drug phase (a device or procedure study).
- Who can join
- Ages 20 years and older. About 38 people. The full rules are on the registry page.
- Where
- China
- When
- Starts or started 1 July 2025, ends 1 June 2027. Registered 10 July 2025.
- Results
- None posted yet.
In the researchers' words
Current evidence and clinical applications of robotic gait training devices for motor function recovery post-stroke are increasingly available. Although existing research demonstrates that robotic gait training can improve patients' gait and balance, there remains a lack of in-depth investigation into its specific mechanisms of action concerning central nervous system (CNS) reorganization - notably, changes in activity within the motor cortex and associated neural networks. The intrinsic changes within the CNS have received insufficient attention, limiting a comprehensive and profound understanding of the rehabilitation outcomes. Therefore, this study aims to elucidate the potential mechanisms underlying robotic gait training-induced neuroplasticity by integrating functional near-infrared spectroscopy (fNIRS) technology with multi-dimensional lower limb motor function assessment tools (such as FAC, BBS, AMEDA, 10MWT, 6MWT, TUGT). It will systematically investigate the effects of robotic gait training on both the central nervous system and lower limb motor function in stroke patients. Furthermore, the study will compare the differences in functional recovery efficacy between robotic gait training and conventional rehabilitation therapies.
Sites
- Shanghai Ruijin Hospital, affiliated to Shanghai Jiao Tong University, School of medicine,Shanghai, Shanghai Municipality, China
