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The Effect of Dexmedetomidine on Postoperative Cognitive Function in Geriatric Patients

NCT07047898 · Ankara Etlik City Hospital · Updated 2 July 2025

What is being tested
The group receiving dexmedetomidine infusion; The group not receiving dexmedetomidine infusion
For
Dexmedetomidine; Robotic Surgery; Geriatric Patients
Kind of study
Tests a treatment or device on volunteers. No drug phase (a device or procedure study).
Who can join
Ages 65 years and older. About 60 people. The full rules are on the registry page.
Where
Turkey (Türkiye)
When
Starts or started Aug 2025, ends 21 Aug 2026. Registered 2 July 2025.
Results
None posted yet.

In the researchers' words

In pelvic surgeries, using laparoscopic surgical procedures provides advantages such as reduced postoperative pain and complications, early mobilization, shorter hospital stays, lower costs, better cosmetic outcomes, and faster return to daily activities. In robotic surgeries, the instruments have superior maneuverability compared to the human wrist, allowing for more precise work in delicate areas with a three-dimensional view while eliminating the surgeon's hand tremor. On the other hand, despite advances in surgical techniques, anesthesia management, and intensive care, a significant proportion of geriatric patients experience cognitive decline after surgery. Postoperative cognitive function decline can reduce the quality of life and lead to significant damage to family and social support systems. Postoperative cognitive dysfunction (POCD), defined as a decline in cognitive function following surgeries performed under general anesthesia, is a common postoperative cognitive impairment, particularly in the elderly population. Studies have shown that the incidence of POCD in individuals aged 60 and above ranges between 20% and 40%. Additionally, POCD is associated with prolonged hospital stays, reduced mobility, and increased mortality. Patients undergoing robotic laparoscopic radical surgery assume the Trendelenburg position, which provides better exposure of the pelvic…
ClinicalTrials.gov, NCT07047898

Sites

  • Ankara Etlik City HospitalYenimahalle, Ankara, Turkey (Türkiye)