Not recruiting yet
Robot-Aided Off-Axis Neuromuscular Training for Knee OA
NCT07014098 · University of Maryland, Baltimore · Updated 28 July 2026
- What is being tested
- Robot-Aided Off-Axis Neuromuscular Training; Traditional elliptical regular stepping
- For
- Osteoarthritis of Knee
- Kind of study
- Tests a treatment or device on volunteers. No drug phase (a device or procedure study).
- Who can join
- Ages 45 years to 85 years. About 36 people. The full rules are on the registry page.
- Where
- Not stated
- When
- Starts or started 1 Sept 2026, ends Jan 2030. Registered 10 June 2025.
- Results
- None posted yet.
In the researchers' words
Although the primary knee motion occurs in flexion/extension, the frontal and transverse (off-axis) knee motions are smaller but crucial for maintaining joint stability and normal knee loading. Altered kinematics and neuromuscular control in off-axis knee motions have been reported in patients with knee osteoarthritis (OA), which are associated with excessive knee loading and the progression of knee OA. However, traditional rehabilitative treatments for people with knee OA and existing exercise equipment often focus on sagittal plane movement. Probably due to the technical limitations, there is a lack of convenient and effective equipment/method to train patients with knee OA in off-axis (frontal and transverse) planes. The purpose of this study is to use a robot-aided elliptical training device to measure knee neuromechanical properties and to improve neuromuscular control in off-axis knee motions, aiming for joint de-loading and pain reduction for individuals with knee OA.