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Under way, not recruiting

Robot-assisted Surgery for Colorectal Cancer Resection: A Population-based Analysis of Prevalence, Trends and Outcomes

NCT06959849 · Medizinische Hochschule Brandenburg Theodor Fontane · Updated 5 Sept 2025

What is being tested
Use of robot surgical system
For
Colorectal Cancer (CRC); Robotic Surgical Procedures; Laparoscopic Abdominal Surgery; Outcome Assessment
Kind of study
Watches patients without assigning a treatment. No drug phase (a device or procedure study).
Who can join
Ages 18 years and older. About 128,000 people. The full rules are on the registry page.
Where
Not stated
When
Starts or started 1 Jan 2016, ends 28 Feb 2026. Registered 7 May 2025.
Results
None posted yet.

In the researchers' words

The objective of this research project is to conduct a comparative analysis of short- and long-term outcomes between conventional laparoscopic and robot-assisted resection procedures for colorectal cancer. The analysis will utilize population-based DRG data and clinical cancer registry data from Germany. The rationale behind this project is that the number of conversions to open surgery in robotic procedures is approximately half that observed in laparoscopic procedures. Furthermore, it has been demonstrated that conversions are associated with a markedly elevated risk of postoperative complications. The aim of this project is to estimate the number of avoidable adverse outcomes resulting from the use of robot-assisted surgery. Multiple studies have shown, that the conversion rate for robot-assisted surgery (RAS) is consistently lower than that for conventional laparoscopic (LAP) surgery. Additionally, conversions have been reported to be associated with an increased risk of adverse surgical outcomes. However, most studies have not achieved statistical significance, due to limited sample sizes and insufficient statistical power. A comprehensive review of the existing literature reveals three key findings. First, the conversion rate for RAS procedures is approximately half that of LAP procedures. Second, conversions are associated with a significantly higher incidence of…
ClinicalTrials.gov, NCT06959849