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Short- and Long-term Effects of Robot-assisted Plication in Diaphragmatic Paralysis

NCT06919185 · Uppsala County Council, Sweden · Updated 11 April 2025

What is being tested
Not stated
For
Diaphragmatic Plication; Diaphragmatic Paralysis; Diaphragmatic Eventration
Kind of study
Watches patients without assigning a treatment. No drug phase (a device or procedure study).
Who can join
Ages 18 years to 85 years. About 50 people. The full rules are on the registry page.
Where
Sweden
When
Starts or started May 2025, ends Dec 2031. Registered 9 April 2025.
Results
None posted yet.

In the researchers' words

Diaphragmatic paralysis may lead to severe symptoms such as breathlessness and reduced physical capacity. Diaphragmatic plication using Robotic-Assisted Thoracic Surgery (RATS) is a minimally invasive surgical technique developed to improve lung function by correcting diaphragmatic elevation. While its benefits have been reported in retrospective reports, prospective studies are lacking. This prospective observational cohort study aimsto evaluate the short- and long-term effects of robot-assisted diaphragmatic plication on subjective breathlessness, physical performance, lung function, blood gases, and imaging findings at five Swedish university hospitals: Gothenburg, Linköping, Lund, Umeå, and Uppsala. Patients will be assessed preoperatively and postoperatively after one to three months and after one and three years.
ClinicalTrials.gov, NCT06919185

Sites

  • Department of Medical Sciences, Lung-, Allergy-, and Sleep Research, Uppsala University/Uppsala University HospitalUppsala, Sweden