Looking for volunteers
PROtective Ventilation With FLOW-Controlled Ventilation
NCT06703814 · Cantonal Hospital of St. Gallen · Updated 21 Oct 2026
- What is being tested
- Intraoperative flow-controlled ventilation strategy; Intraoperative pressure-controlled ventilation strategy
- For
- Postoperative Pulmonary Complications (PPCs); Feasibility Studies; Pilot Study
- Kind of study
- Tests a treatment or device on volunteers. No drug phase (a device or procedure study).
- Who can join
- Ages 18 years and older. About 100 people. The full rules are on the registry page.
- Where
- Austria, Germany, Switzerland (3 sites)
- When
- Starts or started 2 Aug 2025, ends 30 Nov 2026. Registered 25 Nov 2024.
- Results
- None posted yet.
In the researchers' words
The investigators want to investigate in patients undergoing robot-assisted laparoscopic surgery (a minimally invasive procedure) how applicable flow-controlled ventilation is, and whether it might also be safer than the current ventilation techniques, as well as its impact on potentially reducing the risk of lung-specific complications. Flow-controlled ventilation has already been tested in several studies on animals and humans and has proven to be a safe form of ventilation for patients undergoing surgery under general anesthesia. When patients undergo major surgery, general anesthesia is required and, as a result, mechanical ventilation of the lungs. Especially in long and complex surgeries, ventilation can become more difficult or lead to complications postoperatively. These patients may then experience shortness of breath, coughing, or require medication to improve lung function. In some cases, reintubation or additional mechanical ventilation may be necessary for support. Previous human studies have shown that flow-controlled ventilation is less stressful and, therefore, potentially safer for the lungs compared to traditional ventilation techniques, and that less supplemental oxygen is required. This effect and the safety of flow-controlled ventilation have been demonstrated in several studies. Therefore, in this study, the investigators aim to explore whether…
Sites
- Department of Anaesthesiology, Medical University InnsbruckInnsbruck, Tyrol, Austria
- Department of Anesthesiology, Intensive Care and Pain Medicine, BG University Hospital Bergmannsheil, Ruhr-University Bochum, GermanyBochum, Germany, Germany
- Department of Anaesthesiology, Rescue- and Pain Medicine Cantonal Hospital St. GallenSankt Gallen, Canton of St. Gallen, Switzerland
