Monday, October 26, 2026 · Daily editionET --:--:--

Under way, not recruiting

Cryodevitalization for the Treatment of Early Stage Lung Cancer, CRYSTAL Trial

NCT06593106 · Vanderbilt-Ingram Cancer Center · Updated 18 Aug 2026

What is being tested
Cryosurgery; Robotic Bronchoscopy; Bronchoscopy with Biopsy; Resection; Chest Radiography; Computed Tomography; Biospecimen Collection; Electronic Health Record Review
For
Stage I Lung Cancer; Stage II Lung Cancer
Kind of study
Tests a treatment or device on volunteers. No drug phase (a device or procedure study).
Who can join
Ages 18 years and older. About 13 people. The full rules are on the registry page.
Where
United States
When
Starts or started 27 Sept 2024, ends 31 Aug 2027. Registered 19 Sept 2024.
Results
None posted yet.

In the researchers' words

This clinical trial studies side effects and best treatment time of cryodevitalization in treating patients with early stage (stage I or stage II) lung cancer. Cryodevitalization is a type of cryosurgery that uses a flexible probe (cryoprobe) to kill tumor cells by freezing them. It is delivered at the time of standard diagnostic robotic bronchoscopy. Using cryodevitalization may be safe, tolerable and/or effective in treating patients with early stage lung cancer.
ClinicalTrials.gov, NCT06593106

Sites

  • Vanderbilt University/Ingram Cancer CenterNashville, Tennessee, United States