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Superior Hypogastric Nerve Plexus Block With Bupivacaine After Robotic Resection of Endometriosis

NCT06577233 · Baylor College of Medicine · Updated 18 Aug 2025

What is being tested
Bupivacaine Hydrochloride; Normal saline
For
Endometriosis
Kind of study
Tests a treatment or device on volunteers. Phase 4.
Who can join
Ages 18 years to 65 years. About 60 people. The full rules are on the registry page.
Where
United States
When
Starts or started 28 Aug 2024, ends 31 Aug 2025. Registered 29 Aug 2024.
Results
None posted yet.

In the researchers' words

Endometriosis is a condition that causes significant pelvic pain and affects 10-15% of reproductive age women. Treatment options area both medical and surgical for pain relief, however with surgical options, past studies have demonstrated a higher risk of surgical complications as well as higher postoperative pain scores in women with endometriosis. Despite attempts to limit narcotic pain medications with enhanced recovery after surgery (ERAS) protocols, persistent opioid use after surgery is a national crisis, and it is important to explore multimodal options for pain relief. Various studies have shown improvement in pain with use of superior hypogastric nerve blocks in gynecologic surgery, but these effects have not yet been examined in the setting of a minimally invasive endometriosis resection. The goal of this clinical trial is to determine if a superior hypogastric nerve plexus block with 0.25% bupivacaine hydrochloride can decrease postoperative pain and opioid requirements in patients undergoing robotic assisted resection of endometriosis for the first week after surgery. Researchers will perform a superior hypogastric nerve plexus block by either injecting 0.25% bupivacaine hydrochloride (investigative treatment) or normal saline (placebo) in subjects who are undergoing a robotic assisted resection of endometriosis. To determine if postoperative pain is reduced,…
ClinicalTrials.gov, NCT06577233

Sites

  • Texas Childrens Hospital Pavilion for WomenHouston, Texas, United States