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The Effect of Minimally Invasive Surgery on Systemic Inflammatory Response in Rectal Cancer

NCT06540027 · Başakşehir Çam & Sakura City Hospital · Updated 15 Aug 2024

What is being tested
rectal cacer surgery
For
Colorectal Cancer; Colorectal Adenocarcinoma; Rectal Cancer; Rectal Cancer Stage; Immune System Disorder
Kind of study
Watches patients without assigning a treatment. No drug phase (a device or procedure study).
Who can join
Ages Not stated. About 80 people. The full rules are on the registry page.
Where
Turkey (Türkiye)
When
Starts or started 1 June 2024, ends 1 March 2025. Registered 6 Aug 2024.
Results
None posted yet.

In the researchers' words

As a hypothesis and shown in many meta-analyses and randomized controlled studies, minimally invasive surgery causes less surgical trauma and therefore less proinflammatory response and immunosuppression develop, and postoperative recovery is faster. Although various prognostic studies on the relationship between gastrointestinal cancer types and SII (systemic inflammatory index) and the use of minimally invasive surgery have been published, the high level of this response and the type of surgery in the treatment of colorectal cancer have not yet been shown to have a direct effect on SII.
ClinicalTrials.gov, NCT06540027

Sites

  • Yigit DuzkoyluIstanbul, Turkey (Türkiye)