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ExoDoF: Robotic Exoskeleton for Upper Limb Motor Rehabilitation After Stroke

NCT06496529 · University of Chile · Updated 6 Oct 2026

What is being tested
DoF intervention; Task intervention
For
Stroke
Kind of study
Tests a treatment or device on volunteers. No drug phase (a device or procedure study).
Who can join
Ages 18 years to 81 years. About 44 people. The full rules are on the registry page.
Where
Chile (4 sites)
When
Starts or started 1 March 2025, ends 30 June 2027. Registered 11 July 2024.
Results
None posted yet.

In the researchers' words

Two decades ago, the projection of recovery of the upper extremity (UE) after a stroke had a very poor prognosis worldwide. Nowadays, thanks to medical advances and early rehabilitation, the prognosis for recovery has improved; however, there is still a limit that no therapy has been able to overcome, related to spontaneous recovery as part of the natural evolution of the pathophysiological process, rather than with the contribution of rehabilitation. Additionally, existing therapies show partial effectiveness on the recovery of UE function, but do not avoid the use of compensatory strategies or alternatives to normal movement. Given this situation, there is an active search for new therapeutic approaches. In this clinical trial the investigators propose a rehabilitation paradigm that promotes the recovery of control of specific planes of movement through the selective restriction of degrees of freedom, simplifying control demands. The investigators sought to test the hypothesis that people with stroke in the early subacute stage and who present alterations in the movement of the upper extremity, a rehabilitation protocol that reduces the degrees of freedom of the UE and trunk, enables greater recovery of the movement of the UE and less use of compensatory movements compared to a protocol without DoF control. The general objective is to demonstrate the effect of training with…
ClinicalTrials.gov, NCT06496529

Sites

  • Hospital Clínico Universidad de ChileSantiago, Chile
  • Hospital El CarmenSantiago, Chile
  • Hospital San JoséSantiago, Chile
  • Hospital Dr. Hernán Henríquez AravenaTemuco, Chile