Looking for volunteers
German-funded Laparoscopic Approach to Cervical Cancer
NCT06489795 · Hannover Medical School · Updated 3 Feb 2025
- What is being tested
- Laparoscopic or robot-assisted radical/simple hysterectomy; Abdominal radical/simple hysterectomy
- For
- Cervical Cancer
- Kind of study
- Tests a treatment or device on volunteers. No drug phase (a device or procedure study).
- Who can join
- Ages 18 years and older. About 756 people. The full rules are on the registry page.
- Where
- Germany (14 sites)
- When
- Starts or started 17 July 2024, ends Jan 2034. Registered 8 July 2024.
- Results
- None posted yet.
In the researchers' words
The G-LACC trial is a prospective, interventional, multicenter, open-label, randomized and controlled non-inferiority operative trial. The main goal of this clinical trial is to evaluate the non-inferiority of minimally invasive radical hysterectomy in contrast to abdominal radical hysterectomy in patients with early-stage cervical cancer. In the case of SHAPE criteria, surgery may also be performed as minimally invasive or abdominal simple hysterectomy. The primary criterion for assessment is disease-free survival (DFS). As secondary outcomes, overall survival (OS), disease recurrence, quality of life, intra-/postoperative complications, and serious adverse events are recorded for assessment.
Sites
- Ludwigsburg Hospital, Department of Gynecology and ObstetricsLudwigsburg, Baden-Wurttemberg, Germany
- University Medical Center Tübingen, Department of GynecologyTübingen, Baden-Wurttemberg, Germany
- Hochtaunus-Clinics Bad Homburg, Department of GynecologyBad Homburg, Hesse, Germany
- University Medical Center Göttingen, Department of Gynecology and ObstetricsGöttingen, Lower Saxony, Germany
- Hannover Medical School, Department of Gynecology and ObstetricsHanover, Lower Saxony, Germany
- Hospital Lüneburg, Department of GynecologyLüneburg, Lower Saxony, Germany
- Hospital Bielefeld - Center, Department of GynecologyBielefeld, North Rhine-Westphalia, Germany
- University Medical Center Düsseldorf, Department of Gynecology and ObstetricsDüsseldorf, North Rhine-Westphalia, Germany
- Protestant Hospital Wesel, Gynecological Cancer CenterWesel, North Rhine-Westphalia, Germany
- University Medical Center Mainz, Department of Obstetrics and GynecologyMainz, Rhineland-Palatinate, Germany
- University Hospital Schleswig-Holstein, Campus Kiel, Department of Gynecology and ObstetricsKiel, Schleswig-Holstein, Germany
- Vivantes Auguste-Viktoria-Hospital, Department of GynecologyBerlin Schöneberg, State of Berlin, Germany
- Martin Luther Hospital Berlin, Department of Gynecology and ObstetricsBerlin, Germany
- University Medical Center Hamburg-Eppendorf, Department of GynecologyHamburg, Germany