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Using CircuLating Tumor DNA to Risk Adapt Post-Operative Therapy for HPV-associated Oropharyngeal Cancer

NCT06445114 · Zachary Zumsteg · Updated 5 Aug 2026

What is being tested
Cisplatin
For
Oropharyngeal Cancer; Carcinoma
Kind of study
Tests a treatment or device on volunteers. Phase 2.
Who can join
Ages 18 years and older. About 50 people. The full rules are on the registry page.
Where
United States (4 sites)
When
Starts or started 12 May 2025, ends June 2032. Registered 6 June 2024.
Results
None posted yet.

In the researchers' words

This is a single institution phase II study that will enroll patients with T0-3N0-2 p16-positive oropharyngeal squamous cell carcinoma (OSCC) undergoing resection of all gross visible disease at the primary site and in the lymph nodes.
ClinicalTrials.gov, NCT06445114

Sites

  • Cedars-Sinai Cancer at Beverly Hills (THO)Beverly Hills, California, United States
  • Cedars Sinai Medical CenterLos Angeles, California, United States
  • CS Cancer at Valley Oncology Medical GroupTarzana, California, United States
  • CS Cancer at the Hunt Cancer CenterTorrance, California, United States