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Spinal Morphine or Intravenous Lidocaine in Robot-assisted Upper Urologic Surgery

NCT06349668 · Hans Bahlmann · Updated 5 Feb 2026

What is being tested
spinal analgesia with morphine and bupivacaine; lidocaine infusion
For
Other Specified Disorders of Kidney and Ureter; Benign Neoplasm of Ureter; Calculus of Kidney and Ureter; Ureter Cancer; Ureteric Reflux; Congenital Ureteric Anomaly; Benign Renal Neoplasm; Renal Cancer
Kind of study
Tests a treatment or device on volunteers. Phase 3.
Who can join
Ages 18 years and older. About 220 people. The full rules are on the registry page.
Where
Sweden (3 sites)
When
Starts or started 9 April 2024, ends 31 Dec 2027. Registered 5 April 2024.
Results
None posted yet.

In the researchers' words

The goal of this clinical trial is to learn whether the addition of spinal analgesia leads to superior recovery in patients undergoing robotic-assisted laparoscopic upper urinary tract surgery under general anesthesia. The main questions it aims to answer are: * Is the decrease in wellbeing as quantified by the patient-centered outcome scale "Quality of Recovery 15" (QoR-15), from baseline to the first day after surgery (POD 1), at least 8.0 points less in patients receiving spinal analgesia in addition to general anesthesia? * Does spinal analgesia result in improved recovery as quantified by QoR-15 at POD 7, the incidence of postoperative pain at rest and at mobilization, nausea and vomiting, the need for opioid analgesics, time out-of-bed, length of stay and the incidence of complications? * Does spinal analgesia increase workload in the OR, as quantified by time from arrival in the OR to start of surgery? * Does spinal analgesia result in an increased incidence of hypotension and cardiac dysfunction during surgery, as well as an increased incidence of pruritus after surgery? Participants will be randomized to receive either spinal analgesia with bupivacaine and morphine preoperatively or an intravenous infusion with lidocaine intraoperatively. QoR-15 and other markers of recovery will be registered using structured interviews preoperatively, at POD1 and POD7. In…
ClinicalTrials.gov, NCT06349668

Sites

  • Länssjukhuset i KalmarKalmar, Sweden
  • University Hospital LinköpingLinköping, Sweden
  • Centrallasarettet VäxjöVaxjo, Sweden