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Robot-assisted ICG-guided Sentinel Node Biopsy in Testicular Cancer

NCT06133543 · Heinrich-Heine University, Duesseldorf · Updated 15 Sept 2025

What is being tested
Robot-assisted ICG-guided sentinel lymph node biopsy
For
Germ Cell Tumor; Seminoma; Nonseminomatous Germ Cell Tumor
Kind of study
Tests a treatment or device on volunteers. No drug phase (a device or procedure study).
Who can join
Ages 18 years to 99 years. About 44 people. The full rules are on the registry page.
Where
Germany
When
Starts or started 6 Sept 2023, ends 31 March 2028. Registered 15 Nov 2023.
Results
None posted yet.

In the researchers' words

Robot-assisted image-guided sentinel lymph node biopsy (RAISN) in testicular cancer is a novel technique that has not been widely investigated yet. This technique is promising and could be implemented as a future standard in the primary diagnostic work up of clinical stage (CS) I testicular cancer. Current staging strategies have a poor predictive accuracy for occult metastatic disease. So far, feasibility studies used 99mTC-nanocolloid staining and laparoscopy and all patients with tumor-positive nodes received adjuvant systemic treatment. The development of a robot-assisted image-guided lymph node resection technique with indocyanine green (ICG) is potentially more precise, easier to apply and widely available. With this new diagnostic approach the management of newly diagnosed testicular cancer patients might be changed dramatically by reducing overtreatment and treatment-related toxicity with a minimally invasive robot-assisted procedure.
ClinicalTrials.gov, NCT06133543

Sites

  • University Hospital of DuesseldorfDüsseldorf, Germany