Finished
Comparison of Volume-controlled and Pressure-controlled Ventilation in Clasp-knife Position
NCT06056401 · Sun Yat-sen University · Updated 28 Sept 2023
- What is being tested
- record Hemodynamic variables, respiratory variables and arterial blood gas at specific times
- For
- Mechanical Ventilation; General Anesthesia; Urological Surgery; Robotic Surgery
- Kind of study
- Tests a treatment or device on volunteers. No drug phase (a device or procedure study).
- Who can join
- Ages 18 years to 65 years. About 60 people. The full rules are on the registry page.
- Where
- China
- When
- Starts or started 15 Oct 2022, ends 24 Feb 2023. Registered 28 Sept 2023.
- Results
- None posted yet.
In the researchers' words
Carbon dioxide (CO2) pneumoperitoneum and clasp-knife positioning are commonly used to improve surgical access during robot-assisted laparoscopic urological surgery. However, these methods are sometimes associated with several unwanted cardiopulmonary effects such as increased mean arterial pressure, decreased pulmonary compliance and functional residual capacity, increased peak inspiratory pressure, and respiratory acidosis in association with hypercarbia. Volume-controlled ventilation (VCV) is the most commonly used method of ventilation during general anesthesia. It provides fixed minute ventilation and pulmonary resistance, which affect airway pressure. In pressure-controlled ventilation (PCV), constant inspiratory airway pressure can be achieved by decelerating the flow. However, minute ventilation is not fixed . CO2 pneumoperitoneum in the clasp-knife positioning can influence hemodynamic variables, including blood pressure, heart rate, and cardiac output. This is because changes in airway pressure affect intrathoracic pressure and the function of the heart itself. In this randomized study, we investigated the effects of VCV and PCV on peak inspiratory pressure during robot-assisted laparoscopic urological surgery involving CO2 pneumoperitoneum in the clasp-knife position.
Sites
- Cai XinyuanGuangzhou, Guangdong, China
