Monday, October 26, 2026 · Daily editionET --:--:--

Finished

Liposomal Bupivacaine and Transoral Robotic Surgery

NCT05862792 · Geisinger Clinic · Updated 9 Oct 2026

What is being tested
Liposomal bupivacaine
For
Oropharyngeal Cancer; Dysphagia, Oropharyngeal; Post Operative Pain; Transoral Robotic Surgery
Kind of study
Watches patients without assigning a treatment. No drug phase (a device or procedure study).
Who can join
Ages 18 years and older. About 39 people. The full rules are on the registry page.
Where
United States
When
Starts or started 1 June 2023, ends 2 Oct 2025. Registered 17 May 2023.
Results
None posted yet.

In the researchers' words

This study is for patients with oropharyngeal squamous cell carcinoma. We want to learn more about how we can optimize pain control in patients who undergo transoral robotic surgery (TORS) for oropharyngeal squamous cell carcinoma. Our goal is to determine if a local anesthetic called EXPAREL® (Liposomal Bupivacaine) impacts postsurgical pain and swallow function in patients with oropharyngeal squamous cell carcinoma undergoing TORS. EXPAREL® is an FDA-approved anesthetic drug that provides long-lasting and precise pain relief when injected into the surgical wound. Our study team wants to determine if injecting EXPAREL® into the surgical wound will provide better pain relief and swallow function when compared to patients who do not undergo postoperative EXPAREL® injection. Both options for postoperative pain control are considered standard of care for patients undergoing TORS.
ClinicalTrials.gov, NCT05862792

Sites

  • Geisinger Medical CenterDanville, Pennsylvania, United States