Monday, October 26, 2026 · Daily editionET --:--:--

Looking for volunteers

Preop Laxatives in Robotic Urologic Surgery

NCT05805436 · Chad R. Tracy · Updated 30 May 2025

What is being tested
Polyethylene Glycol 3350
For
Prostate Cancer; Kidney Cancer; Constipation
Kind of study
Tests a treatment or device on volunteers. Phase 4.
Who can join
Ages 30 years to 100 years. About 240 people. The full rules are on the registry page.
Where
United States
When
Starts or started 1 June 2023, ends 3 March 2026. Registered 10 April 2023.
Results
None posted yet.

In the researchers' words

Minimally-invasive surgery, either laparoscopic or robotic, is commonly used in urology. Several urologic procedures including prostatectomy, radical nephrectomy, and partial nephrectomy are now commonly performed robotically. Patients undergoing these procedures often have delayed return of bowel function and persistent gastrointestinal symptoms including nausea/vomiting, abdominal distension, and bloating for several days to weeks after surgery. Postoperative stool softeners and laxatives are routinely used in an effort to minimize these symptoms, with varying degrees of success. The aim of this study will be to evaluate whether the use of a preoperative osmotic laxative will be beneficial in improving recovery of bowel function and alleviating postoperative gastrointestinal complaints in patients undergoing these procedures. Patients will be randomized to either receive or not receive three days of polyethylene glycol (PEG, also known as MiraLAX) on the three days before surgery. Patients in both groups will receive the same postoperative bowel regimen including scheduled PEG both in the hospital and upon discharge until first bowel movement. Patients will be given a questionnaire and diary to record their postoperative gastrointestinal symptoms and time to first bowel movement. These questionnaires and diaries will then be analyzed to determine differences in time to first…
ClinicalTrials.gov, NCT05805436

Sites

  • University of Iowa Hospitals & ClinicsIowa City, Iowa, United States