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Multisite Transcranial Direct Current Stimulation to Promote Hand Function Recovery After Stroke

NCT05638464 · Chinese University of Hong Kong · Updated 3 Sept 2024

What is being tested
multisite HD-tDCS EMG-driven robot hand; Sham HD-tDCS EMG-driven robot hand
For
Stroke
Kind of study
Tests a treatment or device on volunteers. No drug phase (a device or procedure study).
Who can join
Ages 18 years and older. About 50 people. The full rules are on the registry page.
Where
Hong Kong
When
Starts or started 13 Aug 2021, ends Dec 2024. Registered 6 Dec 2022.
Results
None posted yet.

In the researchers' words

A novel multisite high definition tDCS (HD-tDCS) in healthy people showed that such network-targeted stimulation could enhance motor excitability beyond traditional stimulation which targeting only one region. It showed that the excitability following multisite HD-tDCS was more than double the increase following conventional tDCS. To consider the various lesion site of different stroke survivors. The electrode placements based on personalized lesion profiles and anatomical features can be determined using finite element modeling, with lesion profiles generated from fMRI and advanced algorithms calculating the current density to maximize the modulation effect. Combining motor network interaction and the new multisite electrode montage may further provide a potential to facilitate stroke recovery.
ClinicalTrials.gov, NCT05638464

Sites

  • Department of Biomedical Engineering, The Chinese University of Hong KongHong Kong, Hong Kong