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The Comparison of Remimazolam With Propofol in Core Body Temperature

NCT05215834 · Wonkwang University Hospital · Updated 14 Feb 2022

What is being tested
Remifentanil
For
Hypothermia; Anesthesia
Kind of study
Tests a treatment or device on volunteers. Phase 4.
Who can join
Ages 19 years to 75 years. About 90 people. The full rules are on the registry page.
Where
South Korea
When
Starts or started 1 March 2021, ends 30 Nov 2021. Registered 31 Jan 2022.
Results
None posted yet.

In the researchers' words

1. Core body temperature is normally tightly regulated to within a few tenths of a degree. The major thermoregulatory defences in humans are sweating, arteriovenous shunt vasoconstriction, and shivering. 2. Inadvertent hypothermia often complicates prolonged surgery. In patients becoming sufficiently hypothermic, reemergence of thermoregulatory vasoconstriction usually prevents further core hypothermia. 3. The extent to which anesthetics reduce the vasoconstriction threshold depends on the type of drug and its concentration.
ClinicalTrials.gov, NCT05215834

Sites

  • Wonkwag UHIksan, South Korea