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Real-time Lymphatic Channel Visualization Improves Bilateral Sentinel Lymph Node Detection in Endometrial Cancer
NCT05191212 · Bakirkoy Dr. Sadi Konuk Research and Training Hospital · Updated 24 Sept 2025
- What is being tested
- indocyanine green
- For
- Endometrial Cancer; Endometrial Neoplasms; Sentinel Lymph Node Biopsy (SLNB)
- Kind of study
- Tests a treatment or device on volunteers. No drug phase (a device or procedure study).
- Who can join
- Ages 18 years to 80 years. About 80 people. The full rules are on the registry page.
- Where
- Turkey (Türkiye)
- When
- Starts or started 13 July 2021, ends 15 Sept 2025. Registered 13 Jan 2022.
- Results
- None posted yet.
In the researchers' words
Endometrial cancer is the most common malignancy of the female genital tract. Standard treatment for early-stage disease includes hysterectomy, bilateral salpingo-oophorectomy, and lymph node assessment. Sentinel lymph node (SLN) mapping with indocyanine green (ICG) has become widely used as an alternative to systematic lymphadenectomy due to lower morbidity and high detection rates. This randomized clinical trial was designed to compare conventional cervical ICG injection with a modified technique, in which injection is continued until real-time lymphatic channels are visualized intraoperatively, for bilateral SLN detection in patients with clinical early-stage endometrial cancer undergoing robotic surgery.
Sites
- Gökhan DemirayakIstanbul, Turkey (Türkiye)