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TMS-based Assessment of Mental Training Effects on Motor Learning in Healthy Participants

NCT04784832 · Institut National de la Santé Et de la Recherche Médicale, France · Updated 20 April 2026

What is being tested
Transcranial magnetic stimulation; Peripheral Nerve Stimulation; Transcranial direct current stimulation; Paired Associative Stimulation; Wrist; Robotic arm; Cervicomedullar stimulation; Physical training; Mental training
For
Motor Learning
Kind of study
Tests a treatment or device on volunteers. No drug phase (a device or procedure study).
Who can join
Ages 18 years to 60 years. About 556 people. The full rules are on the registry page.
Where
France
When
Starts or started 8 April 2024, ends April 2029. Registered 5 March 2021.
Results
None posted yet.

In the researchers' words

The general purpose of this research project is to analyze the specific role of motor imagery on motor learning, assessed through corticospinal excitability measurements and behavioral data collection. This project is based on four sequences. For Sequence 1, the main objective is to examine the effect of mental training on movement speed and accuracy in a manual motor sequence task, as well as the influence of sensory feedback in immediate post-test (i.e., execution of a similar, but not identical, manual motor sequence, other manual tasks) on performance in delayed post-test. The secondary objective will be to examine corticospinal changes (i.e., amplitude of motor evoked potentials) induced by mental training, by measuring the amplitude of motor evoked potentials before and after mental training. For Sequence 2, the main objective is to examine the impact of a motor disturbance induced by a robotic arm at different intervals during the motor imagery process. The secondary objective will be to examine the corticospinal changes (i.e. amplitude of evoked motor potentials) induced by mental training as a function of the applied perturbations, before and after perturbation. For Sequence 3, the main objective will be to examine the influence of neuroplasticity on the quality of mental training. More specifically, the investigators will study the links between brain plasticity and…
ClinicalTrials.gov, NCT04784832

Sites

  • INSERM - U1093 Cognition, Action, and Sensorimotor PlasticityDijon, France