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Real-time Neuromuscular Control of Exoskeletons
NCT04661891 · Shirley Ryan AbilityLab · Updated 14 July 2026
- What is being tested
- Isometric contractions; Isokinetic contractions; Dynamic contractions; Isometric contraction with muscle fatigue; Multi-joint functional activities while wearing exoskeleton; Clinical Assessments
- For
- Stroke
- Kind of study
- Tests a treatment or device on volunteers. No drug phase (a device or procedure study).
- Who can join
- Ages 18 years to 80 years. About 80 people. The full rules are on the registry page.
- Where
- United States
- When
- Starts or started 5 May 2021, ends 15 July 2026. Registered 10 Dec 2020.
- Results
- None posted yet.
In the researchers' words
The purpose of this study is to develop a real-time controller for exoskeletons using neural information embedded in human musculature. This controller will consist of an online interface that anticipates human movement based on high-density electromyography (HD-EMG) recordings, and then translates it into functional assistance. This study will be carried out in both healthy participants and participants post-stroke. The researchers will develop an online algorithm (decoder) in currently existing exoskeletons that can extract hundreds of motor unit (MU) spiking activity out of HD-EMG recordings. The MU spiking activity is a train of action potentials coded by its timing of occurrence that gives access to a representative part of the neural code of human movement. The researchers will also develop a command encoder that can anticipate human intent (multi-joint position and force commands) from MU spiking activity to translate the neural information to movement. The researchers will integrate the decoder with the command encoder to showcase the real-time control of multiple joint lower-limb exoskeletons.
Sites
- Shirley Ryan AbilityLabChicago, Illinois, United States
