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Prophylactic Antibiotics for Urinary Tract Infections After Robot-Assisted Radical Cystectomy

NCT04502095 · Roswell Park Cancer Institute · Updated 29 Sept 2026

What is being tested
Clindamycin; Diary; Ertapenem; Levofloxacin; Nitrofurantoin; Trimethoprim-Sulfamethoxazole
For
Bladder Carcinoma; Refractory Bladder Carcinoma; Urinary Tract Infection
Kind of study
Tests a treatment or device on volunteers. Phase 4.
Who can join
Ages 18 years and older. About 89 people. The full rules are on the registry page.
Where
United States
When
Starts or started 2 Sept 2020, ends 13 March 2025. Registered 6 Aug 2020.
Results
Posted on the registry on 29 Sept 2026.

In the researchers' words

This trial investigates whether a one-month course of preventative (prophylactic) antibiotics helps to reduce urinary tract infections after robot-assisted surgery to remove all of the bladder as well as nearby tissues and organs (radical cystectomy). Urinary tract infections are a common occurrence after robot-assisted radical cystectomy. Antibiotics such as trimethoprim-sulfamethoxazole or nitrofurantoin may prevent or control infections in patients with urinary tract infection and may help improve their response to radical cystectomy. Information gained from this study may help researchers to predict patient complications and identify better ways to manage these complications.
ClinicalTrials.gov, NCT04502095

Sites

  • Roswell Park Cancer InstituteBuffalo, New York, United States