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Multimodal Pain Management After Robotic-Assisted Total Laparoscopic Hysterectomy

NCT04429022 · State University of New York at Buffalo · Updated 1 Aug 2023

What is being tested
Gabapentin; Acetaminophen; Celecoxib; Ketorolac; Paracervical block with ropivacaine; Local anesthetic injection with ropivacaine at abdominal laparoscopic port sites; Hydromorphone; Oxycodone
For
Pain, Postoperative
Kind of study
Tests a treatment or device on volunteers. Phase 3.
Who can join
Ages 25 years to 90 years. About 68 people. The full rules are on the registry page.
Where
United States
When
Starts or started 24 Nov 2020, ends 31 May 2022. Registered 11 June 2020.
Results
Posted on the registry on 1 Aug 2023.

In the researchers' words

Hysterectomy is the most common major gynecologic surgery performed in the US and is performed for a variety of indications including malignancy, pelvic mass, endometriosis, leiomyoma, and pelvic organ prolapse. The traditional regimen for pain control post-operatively is opioid-based however in light of the opioid epidemic, a transition to non-opioid pain medication regimens is desired by both physicians and patients alike. The goal of this study is to develop a multimodal non-opioid pain medication regimen that minimizes postoperative opioid use after robotic assisted total laparoscopic hysterectomy. Historical controls from January, 2017 to January, 2020 will be compared to our treatment arm from November, 2020 to November, 2022. Included in our treatment protocol is paracervical block and local ropivacaine at abdominal incision sites at surgical start, gabapentin and acetaminophen preoperatively and postoperatively, and celecoxib postoperatively. Opioid use will be measured 0-3 h postop and 3-24h postop (as surrogate marker of time spent recovering in the Post Anesthesia Care Unit (PACU), and during the full length of hospital stay); pain scores will additionally be measured.
ClinicalTrials.gov, NCT04429022

Sites

  • Millard Fillmore Suburban HospitalWilliamsville, New York, United States