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Exoskeleton Variability Optimization

NCT04338815 · University of Nebraska · Updated 19 June 2025

What is being tested
Exoskeleton Optimization; Endurance Evaluation
For
Peripheral Arterial Disease
Kind of study
Tests a treatment or device on volunteers. No drug phase (a device or procedure study).
Who can join
Ages 19 years to 85 years. About 9 people. The full rules are on the registry page.
Where
United States
When
Starts or started 31 Jan 2022, ends 28 March 2025. Registered 8 April 2020.
Results
Posted on the registry on 19 June 2025.

In the researchers' words

Exoskeletons, wearable devices that assist with walking, can improve mobility in clinical populations. With exoskeletons, it is crucial to optimize the assistance profile. Recent studies describe algorithms (i.e., human-in-the-loop) to optimize the assistance profile with real-time metabolic measurements. The needed duration of current human-in-the-loop (HITL) algorithms range from 20 minutes to 1 hour which is longer than the average duration that most patients with peripheral artery disease (PAD) can walk. Because of this limited walking duration, it is often not possible for patients with PAD to reach steady-state metabolic cost, which makes these measurements are not useful for optimizing exoskeletons. In this study, investigators intend to develop and evaluate HITL optimization methods for exoskeletons and use the information to design and evaluate a portable hip exoskeleton. Shorter and more clinically feasible HITL optimization strategies based on experiments in healthy adults might allow utilizing these optimization strategies to become available for patient populations such as patients with PAD.
ClinicalTrials.gov, NCT04338815

Sites

  • University of Nebraska OmahaOmaha, Nebraska, United States