Finished
Individual Optimal Positive End-expiratory Pressure During Robot-assisted Laparoscopic Radical Prostatectomy
NCT04085146 · Seoul National University Hospital · Updated 21 Oct 2021
- What is being tested
- Individualized optimal positive end-expiratory pressure; Conventional positive end-expiratory pressure
- For
- Pulmonary Atelectasis, Postoperative
- Kind of study
- Tests a treatment or device on volunteers. No drug phase (a device or procedure study).
- Who can join
- Ages 20 years and older. About 60 people. The full rules are on the registry page.
- Where
- South Korea
- When
- Starts or started 19 Nov 2019, ends 7 Aug 2020. Registered 11 Sept 2019.
- Results
- None posted yet.
In the researchers' words
During robot-assisted radical prostatectomy, pneumoperitoneum with Trendelenburg position is used. However, perioperative atelectasis and respiratory complications may occur with high incidence due to general anesthesia and carbon dioxide pneumoperitoneum. Intraoperative ventilatory strategy to address these issues include intraoperative recruitment maneuver and positive end-expiratory pressure (PEEP). Recently, individualized optimal PEEP with minimal driving pressure or maximal respiratory compliance was reported to reduce respiratory complications after general anesthesia. A recent version of general anesthesia ventilator provides a stepwise procedure of determining optimal PEEP by calculating respiratory compliance. We investigated whether the application of individualized optimal PEEP could reduce the incidence of atelectasis and respiratory complications after robot-assisted laparoscopic radical prostatectomy compared to uniform PEEP.
Sites
- Seoul National University HospitalSeoul, South Korea
