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Cytokine-guided Robotic Cystectomy

NCT03982498 · East and North Hertfordshire NHS Trust · Updated 16 Dec 2020

What is being tested
Not stated
For
Cancer
Kind of study
Watches patients without assigning a treatment. No drug phase (a device or procedure study).
Who can join
Ages 40 years to 75 years. About 20 people. The full rules are on the registry page.
Where
United Kingdom
When
Starts or started 17 Dec 2018, ends 14 June 2022. Registered 11 June 2019.
Results
None posted yet.

In the researchers' words

There is a recognised complication of surgery known as a 'Paralytic Ileus', where bowel function is reduced after an operation, causing an obstruction and resulting in nausea and vomiting. This complication is more common in patients that have robotic surgery due to the positioning required and the gas pressures required for keyhole/robotic surgery. While some of the factors involved in a paralytic ileus are known, the full mechanism and the chemicals involved are not yet fully understood. This study is looking at the level of specific chemicals called 'cytokines', and the changes in the level of these cytokines in the blood before and after robotic surgery, specifically during bladder removal (cystectomy). Cytokine levels will be compared against post-operative recovery and whether a paralytic ileus is developed.
ClinicalTrials.gov, NCT03982498

Sites

  • East and North Hertfordshire NHS TrustStevenage, Hertfordshire, United Kingdom