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Nivolumab, Ipilimumab and OTSGC-A24 Therapeutic Peptide Vaccine in Gastric Cancer - a Combination Immunotherapy Phase Ib Study.

NCT03784040 · National University Hospital, Singapore · Updated 8 April 2019

What is being tested
OTSGC-A24; Nivolumab; Ipilimumab
For
Gastric Cancer
Kind of study
Tests a treatment or device on volunteers. Phase 1.
Who can join
Ages 21 years to 99 years. About 40 people. The full rules are on the registry page.
Where
Singapore
When
Starts or started 21 Feb 2019, ends 1 March 2024. Registered 21 Dec 2018.
Results
None posted yet.

In the researchers' words

The primary hypothesis is that cancer vaccine can convert non-immunogenic gastric cancer into immunogenic phenotype susceptible to PD1 inhibition. This would lead to an improved radiological response rate and favorable immune contexture for immune checkpoint blockade
ClinicalTrials.gov, NCT03784040

Sites

  • National University HospitalSingapore, Singapore