Finished
TORS De-Intensification Protocol Version 2.0: Dose and Volume Reduction in the Neck
NCT03729518 · Abramson Cancer Center at Penn Medicine · Updated 22 July 2026
- What is being tested
- Radiation Therapy (IMRT or IMPT)
- For
- Oropharyngeal Cancer; Squamous Cell Carcinoma; Human Papilloma Virus
- Kind of study
- Tests a treatment or device on volunteers. No drug phase (a device or procedure study).
- Who can join
- Ages 18 years and older. About 150 people. The full rules are on the registry page.
- Where
- United States
- When
- Starts or started 11 Oct 2018, ends 15 July 2026. Registered 2 Nov 2018.
- Results
- None posted yet.
In the researchers' words
This is a single-arm Phase II study of adjuvant radiation for locally advanced p16+ oropharyngeal squamous cell carcinoma. The main purpose of this research is to determine the likelihood of cancer growing back in the throat or in the neck two years after completion of radiation if lower doses of radiation are used to a smaller area of the head and neck region than is currently used in standard of care.
Sites
- University of PennsylvaniaPhiladelphia, Pennsylvania, United States