Stopped early
Efficacy Between Serratus Plane Block And Local Infiltration In Vats
NCT03642457 · Icahn School of Medicine at Mount Sinai · Updated 30 Sept 2020
- What is being tested
- Bupivacaine; Bupivacaine liposome
- For
- Lung Cancer
- Kind of study
- Tests a treatment or device on volunteers. Phase 4.
- Who can join
- Ages 18 years to 75 years. About 65 people. The full rules are on the registry page.
- Where
- United States (2 sites)
- When
- Starts or started 1 March 2018, ends 31 Dec 2018. Registered 22 Aug 2018.
- Results
- Posted on the registry on 18 Aug 2020.
In the researchers' words
Robotic video-assisted thoracoscopic surgery (VATS) is increasingly being used as it is a less invasive surgery compared to traditional methods, but the acute pain at an early stage after VATS has a major impact on perioperative outcomes. Effective post operative analgesia is believed to reduce morbidity, quicken recovery, improve patient outcome and reduce hospital costs. The site and extent of the incision influences the degree of pain due to disruption of intercostal nerves as well as inflammation of chest wall and pleura. Neuraxial and systemic opioids have been a gold standard as a part of multimodal analgesia for thoracic surgeries. Numerous modalities have been studied: thoracic paravertebral nerve blocks, thoracic epidural analgesia, intercostal nerve blocks, patient controlled analgesia (PCA), cryo-analgesia, transcutaneous electrical nerve stimulation (TENS), inter-pleural blocks, stellate ganglion blocks, long thoracic nerve blocks, and infiltration under direct vision by the surgeon. Serratus plane block is an emerging regional technique that has proven to be effective in comparison to paravertebral blocks in patients undergoing breast surgery and mastectomy with reduced perioperative opioid consumption and improved pain scores. The lateral pectoral nerve, medial pectoral nerve, intercostal nerves and long thoracic nerve are all targets for the serratus plane…
Sites
- Mount Sinai St. Luke's HospitalNew York, New York, United States
- Mount Sinai West HospitalNew York, New York, United States
