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Postoperative Pain, Recovery and Discharge Following Robot-assisted Laparoscopic Prostatectomy

NCT03639389 · Karolinska Institutet · Updated 22 June 2022

What is being tested
Bupivacaine; Analgesics
For
Radical Prostatectomy; Postoperative Pain
Kind of study
Tests a treatment or device on volunteers. Phase 3.
Who can join
Ages 45 years to 85 years. About 211 people. The full rules are on the registry page.
Where
Sweden (2 sites)
When
Starts or started 1 Jan 2019, ends 29 March 2022. Registered 21 Aug 2018.
Results
None posted yet.

In the researchers' words

Prostate cancer is the commonest cancer form in men in Northern Europe. Management of the cancer often includes surgical removal of the primary tumor. In the last 5-10 years, robot assisted laparoscopic prostatectomy (RALP) has become common. Good pain relief is central to early mobilization and greater patient satisfaction. Randomized controlled studies on pain relief following RALP are few and the role of spinal analgesia in pain management following robotic surgery has not been described. Techniques available for pain relief following RALP include spinal anesthesia with or without opiates, intravenous analgesia with morphine or a multimodal pain management technique using a combination of several analgesics. Spinal anesthesia and analgesia reduces the surgical stress and inflammatory response following laparoscopic colorectal surgery and may offer similar benefit even during RALP. Early perioperative complications may cause postoperative morbidity following robotic surgery, and sometimes delay home discharge. Since all robotic operations in the pelvic region are performed in a deep Trendelenberg position, this can even have negative consequences for the heart, brain and the lungs. Cardiac complications in the form of minimal cardiac injury or mild heart failure have not been previously studied following RALP. Additionally, patients are sometimes delirious in the early…
ClinicalTrials.gov, NCT03639389

Sites

  • Karolinska Hospital, SolnaStockholm, Sweden
  • Capio St Görans HospitalStockholm, Sweden