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Influence of Different PEEP Levels and Tidal Volumes on Regional Lung Function

NCT03326414 · Universitätsklinikum Hamburg-Eppendorf · Updated 31 Oct 2017

What is being tested
Constant PEEP - low tidal volume; Constant PEEP - high tidal volume; constant tidal volume - low PEEP; constant tidal volume - high PEEP
For
Pulmonary Ventilation; Newborn, Abnormal
Kind of study
Tests a treatment or device on volunteers. No drug phase (a device or procedure study).
Who can join
Ages 18 years and older. About 40 people. The full rules are on the registry page.
Where
Germany
When
Starts or started Jan 2018, ends June 2018. Registered 31 Oct 2017.
Results
None posted yet.

In the researchers' words

Mechanical ventilation is indispensable for most of surgical interventions but can induce lung injury even in pulmonary healthy patients. This can lead to postoperative pulmonary complications. These adverse effects could be prevented by a better monitoring of intraoperative lung function. Electrical impedance tomography is able to visualize aeration within the lung in real time. The planned study investigates the influence of different levels of positive endexspiratory pressure and different tidal volumes on the aeration.
ClinicalTrials.gov, NCT03326414

Sites

  • Department of Anaesthesiology Center of Anaesthesiology and Intensive Care Medicine University Medical Center Hamburg-Eppendorf University of HamburgHamburg, Germany