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Laser Fluorescence in Cancer Surgical Treatment

NCT03021200 · Instituto do Cancer do Estado de São Paulo · Updated 12 Nov 2019

What is being tested
Green indocianine
For
Esophageal Cancer; Gastric Cancer; ColoRectal Cancer; Prostatic Neoplasms; Uterine Cancer; Head and Neck Cancer; Breast Neoplasm
Kind of study
Tests a treatment or device on volunteers. No drug phase (a device or procedure study).
Who can join
Ages 18 years and older. About 270 people. The full rules are on the registry page.
Where
Brazil
When
Starts or started 12 July 2016, ends 10 Dec 2020. Registered 13 Jan 2017.
Results
None posted yet.

In the researchers' words

The use of fluorescence for real-time evaluation of organ and tissue vascularization and lymph node anatomy is a recent technology with potential for the surgical treatment of cancer. The real-time analysis of tissue vascularization allows immediate identification to the surgeon of areas with greater or lesser blood circulation, favoring surgical decision making and prevention of complications related to tissue ischemia (necrosis, dehiscences and infections). It is a technology with potential application in the areas of Digestive Surgery, Repairing Plastic Surgery in Oncology, Head and Neck Surgery. In addition, fluorescence can be used as a method to identify lymph node structures of interest in the oncological treatment of patients with urologic, gynecological and digestive tumors. Introduced by Pestana et al. In the late 2000s, the perfusion mapping system through intraoperative indocyanine assisted laser angiography (SPY Elite System © LifeCell Corp., Branchburg, N.J.) had its initial application in repairing surgery after breast cancer treatment. The method proved to be useful in the prevention of ischemic and infectious complications in cancer surgery. Pestana, in a prospective clinical series of 29 microsurgical flaps used in several reconstructions, observed a single case of partial loss of the flap, the present technology having a relevant role in intraoperative…
ClinicalTrials.gov, NCT03021200

Sites

  • Ulysses Ribeiro JuniorSão Paulo, São Paulo, Brazil