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Robotic Surgery After Focal Ablation Therapy

NCT03011606 · Queen Mary University of London · Updated 27 Jan 2020

What is being tested
Robotic Surgery
For
Prostate Cancer
Kind of study
Tests a treatment or device on volunteers. No drug phase (a device or procedure study).
Who can join
Ages 18 years and older. About 24 people. The full rules are on the registry page.
Where
United Kingdom (2 sites)
When
Starts or started Feb 2016, ends 21 Oct 2019. Registered 5 Jan 2017.
Results
None posted yet.

In the researchers' words

The toxicity of traditional prostate cancer therapies including radical surgery and external beam radiation is well known. This has prompted a move towards focal therapy where only the cancerous part of the prostate is treated. To date, studies have demonstrated very promising outcomes following focal therapy with the majority of men maintaining their urinary and sexual function after therapy. In a small proportion of men, disease recurs after focal therapy. The optimal treatment for men with recurrent disease after focal therapy is yet to be defined. Patients may undergo further focal therapy to the recurrent disease, undergo radiation therapy, whole-gland therapy using a minimally invasive approach such as High Intensity Focused Ultrasound (HIFU) or cryotherapy. Alternatively patients may undergo radical surgery where the whole prostate is removed. To date, the side-effects or toxicity of any treatment for recurrent prostate cancer after focal therapy has not been formally studied. Traditionally, the side effects of surgery and radiation therapy performed in patients that have already undergone previous prostate cancer treatment have been considerable with high rates of urinary incontinence and erectile dysfunction. However, as focal therapy leaves a significant area of the prostate untreated, the investigators believe surgery after focal prostate therapy will be…
ClinicalTrials.gov, NCT03011606

Sites

  • Guys and St Thomas' Hospital, LondonLondon, United Kingdom
  • University College London HospitalLondon, United Kingdom