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TAP vs Surgical Infiltration of Local Anesthetic in Laparoscopic and Robotic Hysterectomy

NCT02519023 · University of Minnesota · Updated 8 Feb 2019

What is being tested
Liposomal Bupivacaine; Bupivacaine; Ultrasound; Epinephrine; acetaminophen; ibuprofen; Oxycodone
For
Acute Pain
Kind of study
Tests a treatment or device on volunteers. Phase 4.
Who can join
Ages 18 years and older. About 87 people. The full rules are on the registry page.
Where
United States
When
Starts or started July 2016, ends June 2017. Registered 10 Aug 2015.
Results
Posted on the registry on 5 Dec 2018.

In the researchers' words

Laparoscopic and Robotic assisted hysterectomy is a surgical procedure that is a minimally invasive way in which to remove the uterus, which has less scarring and fewer complications. However, this procedure, much like its open-surgical counterpart, is often associated with significant post-operative pain. To augment this pain there are many different analgesic techniques available to offset pain. Ultrasound-guided transversus abdominis plane (TAP) block is one such procedure involving the injection of a local anesthetic into the plane of the transversus abdominal muscle where the terminal branches of nerves lie. A similar, yet different analgesic approach is that of direct injection of local anesthetic into the incision by the surgeon during or just after surgical procedures. These two approaches have both been proven to decrease post-operative pain in patients for many procedures, but never compared to one another.
ClinicalTrials.gov, NCT02519023

Sites

  • University of MinnesotaMinneapolis, Minnesota, United States