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Deep Neuromuscular Blockade During Robotic Radical Prostatectomy
NCT02513693 · Palacky University · Updated 3 Aug 2015
- What is being tested
- Standard neuromuscular blockade; Deep neuromuscular blockade
- For
- Neuromuscular Blockade
- Kind of study
- Tests a treatment or device on volunteers. Phase 4.
- Who can join
- Ages 19 years and older. About 80 people. The full rules are on the registry page.
- Where
- Czechia (2 sites)
- When
- Starts or started July 2015, ends March 2016. Registered 3 Aug 2015.
- Results
- None posted yet.
In the researchers' words
Basic requirement for safe performance of the robotic intra-abdominal surgery is a calm and clear surgical field after the introduction of a capnoperitoneum. That can be enabled by a neuromuscular blockade. Provision of standard neuromuscular blockade is a compromise between optimal surgical conditions (sufficiently deep block) and capability to antagonize the block rapidly at the end of the surgery. With rocuronium, it is possible to maintain deep neuromuscular blockade safely until the very end of the surgery, and unlike with spontaneous recovery or reversal of the block with neostigmine, administration of sugammadex at the end of the surgery will enable quick and consistent reversal of the block. Project is focused on comparison of the parameters of deep and standard neuromuscular blockade - surgical conditions (primary endpoint), quality of recovery and turnover time (secondary endpoints).
Sites
- Dept. of Anesthesiology and Intensive Care Medicine, University Hospital OlomoucOlomouc, Czechia
- Dept. of Anesthesiology, Perioperative Medicine and Intensive Care, J. E. Purkinje University, Masaryk HospitalÚstí nad Labem, Czechia
