Withdrawn before it began
e-PAT Neuromod Evaluation of Personalized rTMS for Resistant Depression
NCT02410421 · University Hospital, Strasbourg, France · Updated 5 Jan 2016
- What is being tested
- Functional magnetic resonance imaging used to individualize rTMS protocol using robotic coil positioning
- For
- Depressive Disorder; Treatment-Resistant
- Kind of study
- Tests a treatment or device on volunteers. Phase 2.
- Who can join
- Ages 18 years to 65 years. The full rules are on the registry page.
- Where
- Not stated
- When
- ends May 2020. Registered 7 April 2015.
- Results
- None posted yet.
In the researchers' words
Although repetitive trans-cranial magnetic stimulation (rTMS) is an effective therapy for resistant depression, it still fail to remit up to 70% of these patients. We hypothesize that personalizing the procedure using functional MRI to better select dysfunctional regions and robotic coil placement to stimulate these regions homogeneously, will increase its efficacy. Individualized rTMS will be compared to traditional rTMS procedure and to trans-cranial direct current stimulation (tDCS). In this small proof of principle study our primary outcome measure will be the correction of the MRI anomalies. Symptoms reduction and the proportion of remitters will be secondary outcome measurements.