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Laser Ablation of Abnormal Neurological Tissue Using Robotic NeuroBlate System
NCT02392078 · Monteris Medical · Updated 24 April 2025
- What is being tested
- NeuroBlate System
- For
- Metastatic Brain Tumor; Primary Brain Tumor; Epileptic/Seizure Foci; Movement Disorders
- Kind of study
- Watches patients without assigning a treatment. No drug phase (a device or procedure study).
- Who can join
- Ages Not stated. About 1,153 people. The full rules are on the registry page.
- Where
- United States (26 sites)
- When
- Starts or started Oct 2015, ends 30 Sept 2023. Registered 18 March 2015.
- Results
- Posted on the registry on 24 April 2025.
In the researchers' words
The NeuroBlate® System (NBS) is a minimally invasive robotic laser thermotherapy tool that is being manufactured by Monteris Medical. Since it received FDA clearance in May 2009, the NBS has been used in over 2600 procedures conducted at over 70 leading institutions across United States. This is a prospective, multi-center registry that will include data collection up to 5 years to evaluate safety, QoL, and procedural outcomes including local control failure rate, progression free survival, overall survival, and seizure freedom in up to 3,000 patients and up to 50 sites.
Sites
- Barrow Neurological Institute at Dignity Health St. Joseph's Hospital & Medical CenterPhoenix, Arizona, United States
- University of Arkansas for Medical SciencesLittle Rock, Arkansas, United States
- University of California, San DiegoLa Jolla, California, United States
- Children's Hospital of Orange CountyOrange, California, United States
- Yale University School of MedicineNew Haven, Connecticut, United States
- Advent Health OrlandoOrlando, Florida, United States
- Johns Hopkins All Children's HospitalSt. Petersburg, Florida, United States
- The Cleveland Clinic FloridaWeston, Florida, United States
- Northwestern UniversityChicago, Illinois, United States
- University of Kansas Medical CenterKansas City, Kansas, United States
- University of LouisvilleLouisville, Kentucky, United States
- Norton Cancer InstituteLouisville, Kentucky, United States
- University of MinnesotaMinneapolis, Minnesota, United States
- United Children's Hospital St. PaulSaint Paul, Minnesota, United States
- Washington UniversitySt Louis, Missouri, United States
- New York University Langone Medical CenterNew York, New York, United States
- Icahn School of Medicine at Mount SinaiNew York, New York, United States
- Duke University Medical CenterDurham, North Carolina, United States
- Wake ForestWinston-Salem, North Carolina, United States
- University Hospitals Cleveland Medical CenterCleveland, Ohio, United States
- Cleveland Clinic FoundationCleveland, Ohio, United States
- Geisinger Medical CenterDanville, Pennsylvania, United States
- University of Pittsburgh Medical CenterPittsburgh, Pennsylvania, United States
- Saint Thomas West Hospital and Research InstituteNashville, Tennessee, United States
- University of Texas Southwestern Medical CenterDallas, Texas, United States
- MD AndersonHouston, Texas, United States