Finished
Preop Dexmedetomidine Attenuates Haemodynamic Responses to Hydrodissection
NCT02102139 · Seoul National University Hospital · Updated 2 April 2014
- What is being tested
- DXM + Propofol; Saline + Propofol
- For
- Robotic Thyroidectomy
- Kind of study
- Tests a treatment or device on volunteers. Phase 4.
- Who can join
- Ages 20 years to 65 years. About 41 people. The full rules are on the registry page.
- Where
- South Korea
- When
- Starts or started May 2012, ends Sept 2012. Registered 2 April 2014.
- Results
- None posted yet.
In the researchers' words
Percutaneous tunnelling (hydrodissection) in the neck and anterior chest in patients undergoing robotic thyroidectomy leads to significant haemodynamic responses such as increases in blood pressure and heart rate. The investigators evaluated whether a single preoperative dexmedetomidine injection attenuated the haemodynamic responses to hydrodissection by reducing the half-maximal effective concentration (EC50) of remifentanil needed to maintain haemodynamic stability during hydrodissection.
Sites
- Seoul National University of HospitalSeoul, South Korea